Table 1 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer

Key Points

• Targeting PPARδ may significantly reduce metastasis in pancreatic cancer models, highlighting its role.
• Pharmacologic intervention showed notable effects on the metastatic process in pancreatic cancer, reducing tumor spread.
• The approach involved pharmacologic targeting to modulate the metabolic response to microenvironmental cues.
• Understanding PPARδ's function could lead to new therapeutic strategies, emphasizing its importance in cancer treatment.