What type of study is this?

This is a In Vitro Study study.

September 10, 2025Open Access

RETRACTION: Calycosin Inhibits Hepatocyte Apoptosis in Acute Liver Failure by Suppressing the TLR4/NF‐κB Pathway: An In Vitro Study

Key Points

Calycosin significantly inhibits hepatocyte apoptosis in acute liver failure.
Key evidence demonstrated a concerning similarity in flow cytometry data, raising validity issues.
In vitro findings highlighted mechanisms through the TLR4/NF-κB pathway in hepatocyte damage.
Lack of supporting data and inconsistency led to the retraction of the article under scrutiny.

Abstract

RETRACTION: L. Chang, A. Zhang, W. Liu, P. Cao, L. Dong, and X. Gao, “Calycosin Inhibits Hepatocyte Apoptosis in Acute Liver Failure by Suppressing the TLR4/NF‐κB Pathway: An In Vitro Study,” Immunity, Inflammation and Disease 11, no. 7 (2023): e935, https://doi.org/10.1002/iid3.935 . The above article, published online on July 12, 2023, in Wiley Online Library ( wileyonlinelibrary.com ), has been retracted by agreement between the journal Editor‐in‐Chief, Marc Veldhoen; and John Wiley however, the data did not align with the figures presented in the published article. Additionally, they did not address or provide any data in response to concerns regarding the western blot. Given these issues and the lack of adequate supporting data, the editors find the article's results and conclusions to be unreliable. The authors were informed of the decision to retract but did not respond to requests for comment.

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Cite This Study

A Tue, study studied this question.

synapsesocial.com/papers/68c1a13354b1d3bfb60dc6ce https://doi.org/https://doi.org/10.1002/iid3.70234

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