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This is a Literature Review study.

September 16, 2025Open Access

Update Gender Affirming Care in Adolescents with Gender Incongruence – Evidence Review and Clinical Implications Considering new Guidelines in different European Countries

Key Points

The review highlights the need for careful consideration of medical interventions in adolescents, as the evidence remains limited.
Guidelines from various European countries emphasize the balance of risks and benefits for adolescents experiencing gender incongruence.
Psychosocial support is reinforced as a vital component of care for adolescents struggling with gender dysphoria during this critical development phase.
The ethical principle of self-determination must align with safe and effective approaches to treatment in young people.

Abstract

Abstract Recently, there have been wide-ranging debates about gender affirming treatment for young people with gender incongruence. The ethical principle of self-determination of young people must be reconciled with a careful assessment and weighing up of the risks and benefits of medical treatment steps. The focus is on psychosocial support for young people struggling with gender incongruence in adolescence. The evidence for the effectiveness of medical interventions in adolescence is still limited. Nevertheless, there is a great need among affected adolescents. In a literature review and based on international debates, guidelines and treatment recommendations, a cautious and balanced approach to the question of the right support for adolescents with gender dysphoria is recommended. Disclosure of Interest None Declared

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