What type of study is this?

This is a Quantitative Study study.

September 17, 2025

The comprehensive Subcortical Atlas of the Human Brain (“SAHB”) derived from high-resolution multimodal MRI at 7T.

Key Points

Detailed 3D subcortical atlas was created, enabling precise localization of deep brain structures essential for various clinical applications.
Using high-resolution MAP-MRI at 7T, the atlas achieved a remarkable resolution of 250 μm, aiding in the segmentation of complex brain areas.
The study incorporated a registration to an in vivo MNI template, facilitating the use of the atlas in functional MRI studies and within different species.
The findings highlight the importance of accurate subcortical mapping for neuroimaging, neurosurgery, and understanding brain function relationships.

Abstract

Motivation: To develop a detailed 3D atlas to help locate the subcortical subregions for anatomical, functional, and clinical studies. Goal(s): To generate the comprehensive subcortical atlas of the human brain, using multimodal MRI ex vivo at 7T, and register it to an in vivo MNI template for 3D segmentation. Approach: Obtained high-resolution images from the fixed brainstem at 7T using MAP-MRI with 250 μm resolution. Results: MAP-MRI enabled detailed noninvasive segmentation of deep brain structures at a high spatial resolution. Impact: Tracing and validating subcortical regions in 3D are imperative for neurosurgical planning for DBS, fMRI studies, cross-species comparison, and establishing brain structure-function relationships.

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Cite This Study

Saleem et al. (Tue,) studied this question.

synapsesocial.com/papers/68d4597b31b076d99fa5ca99 https://doi.org/https://doi.org/10.58530/2025/4780

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