What type of study is this?

This is a Quantitative Study study.

September 17, 2025

Resting-state functional connectivity in mouse cervical spinal cord at 15.2T

Key Points

Resting-state functional circuits were robustly detectable within gray matter in the mouse spinal cord, indicating significant findings.
BOLD signals were effectively measured using 15.2T MRI, highlighting unique characteristics of mouse spinal connectivity.
The study calculated inter-voxel correlations to delineate networks, analogous to those observed in other species.
Findings suggest opportunities for utilizing mouse models in understanding various disorders through detected spinal cord networks.

Abstract

Motivation: Resting-state functional connectivity in mice spinal cord has not been reported previously Goal(s): To identify resting-state functional circuits within the spinal cord of mice Approach: We used 15.2T MRI to detect the intrinsic BOLD signals in mouse spinal cords and calculated inter-voxel correlations in a resting state to delineate networks Results: We found resting-state functional circuits were robustly detectable within gray matter in the mouse spinal cord similar to those reported for other species. Impact: This work shows the potential to detect BOLD signals in mouse spinal cords and derive network characteristics in mouse models of different disorders.

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Cite This Study

Lee et al. (Tue,) studied this question.

synapsesocial.com/papers/68d45b0b31b076d99fa5d31a https://doi.org/https://doi.org/10.58530/2025/0827

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