Gut microbial clusters in children show different cardiometabolic responses to wholegrains – a post hoc analysis of a randomized wholegrain trial in children | Synapse
September 18, 2025Open Access
Gut microbial clusters in children show different cardiometabolic responses to wholegrains – a post hoc analysis of a randomized wholegrain trial in children
Key Points
Gut microbial clusters influenced responses to wholegrain intake, specifically affecting body fat and HDL cholesterol levels.
Children with varying gut microbiomes showed different impacts from wholegrain consumption on cardiometabolic markers.
Analysis from a randomized trial revealed a connection between diet and gut microbiota diversity in children.
These findings point to the significance of microbiome considerations in dietary recommendations for children.
Abstract
Gut microbial clusters in children modified the effects of wholegrain intake on body fat and HDL cholesterol, suggesting a microbiome-driven response to diet.