August 19, 2024Open Access

Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients

Key Points

Key points are not available for this paper at this time.

Abstract

Deletions and partial losses of chromosome 7 (chr7) are frequent in acute myeloid leukemia (AML) and are linked to dismal outcome. However, the genomic landscape and prognostic impact of concomitant genetic aberrations remain incompletely understood.

Read Full Paperexternally

Perguntar à IA

Bookmark

View Full Paper

Cite This Study

Halik et al. (Mon,) studied this question.

synapsesocial.com/papers/68e5bb23b6db643587553246 https://doi.org/https://doi.org/10.1186/s13045-024-01590-1

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition2017 · 1,669 citations
2Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma2011 · 330 citations
3CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia2012 · 159 citations
4Monosomy 7 and deletion 7q in children and adolescents with acute myeloid leukemia: an international retrospective study2007 · 154 citations
5Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes2020 · 639 citations

Perguntar à IA

Bookmark

View Full Paper