Development of in vivo human brain multifrequency DTIMRE (mDTIMRE)

Simultaneous acquisition of diffusion tensor imaging and multifrequency magnetic resonance elastography was examined in this preliminary study on in vivo human brain. The mDTIMRE was achieved by ensuring the same diffusion encoding using experiment parameters with different mechanical frequencies, while fulfilling the timing condition of simultaneous acquisition. By applying a multifrequency dual elasto-visco inversion approach, the effective image resolution of mechanical property maps is improved and enables quantitatively assessment of tissue properties in brain sub-regions. The experiment results show a good correlation between mDTIMRE and conventional measurements.