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Very few segmentation techniques are optimized for 7T images. Due to the lack of approaches and the high level of inhomogeneity observed with Ultra-High Field images, neuroscientists typically limit the analysis to the upper half of the brain. A novel resolution- and contrast-agnostic technique, called SynthSeg, may remedy this limitation. A multi-parameter mapping protocol and MPRAGE images were acquired to test SynthSeg against FreeSurfer on 7T sub-millimeter brain images. Our results showed that SynthSeg can surpass FreeSurfer, especially for the cerebellum and temporal lobes. Moreover, we showed that quantitative maps can be great surrogates to high-resolution T1w images like MPRAGE.
Fortin et al. (Wed,) studied this question.
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