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Multi-shot echo planar imaging (EPI) can be used to reduce spatial distortion and improve spatial resolution in diffusion-weighted imaging; however, patient motion between shots can result in large intra-shot phase differences and increased artifact. It is unknown whether multiplexed sensitivity encoding (MUSE) can be applied to reduce these phase differences in DW-EPI images acquired at low field due to the inherently lower SNR. In this work we evaluate the performance of MUSE in DW-EPI data acquired at 0.5T, in terms of SNR and ghost-to-noise ratio (GNR) as a function of signal averaging, and demonstrate that multi-shot DW-EPI is feasible.
Klassen et al. (Wed,) studied this question.
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