1298-P: Increased Fasting Glucagon-Like Peptide-1 Level Is Associated with Higher Triglyceride–Glucose Index in Type 2 Diabetes Mellitus Patients with Hypertriglyceridemia

Introduction Β=1.58, p=0.047, respectively). Conclusion: In T2DM patients with hypertriglyceridemia, increased fGLP-1 was associated with higher IR as measured by TyG index. FGLP-1 was not related to glucose as a parameter of the TyG index, but fGLP-1 was significantly associated with fasting triglyceride. Increased fGLP-1 secretion may play a compensatory role in the pathogenesis of IR induced by hypertriglyceridemia. Disclosure S. Chong: None. N. Sukor: None. S.A. Robert: None. K. Ng: None. N.A. Kamaruddin: Speaker's Bureau; Boehringer-Ingelheim, Novo Nordisk, AstraZeneca. Funding University Kebangsaan Malaysia (GUP-2017-066); Malaysian Endocrine and Metabolic Society (L12-MEMS6)