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Introduction 180 mg/dl, TAR250 mg/dl and time below range (TBR)70 mg/dl. ANCOVA was used, adjusted for baseline value to determine the relation between group and outcome, and report p-values of the interaction term, group*time. Exercise was evaluated by senior fitness test and assessed by Hedge’s g effect size. Results: Twenty-four patients with T2D completed the trial. Non-statistically significant reductions in glucose metrics were seen. HbA1c decreased by 2.2% (DAT) vs 1.1% (SoC) (-1.1%, -0.2, -1.8, p=0.076). TIR 70-180 mg/dL increased 17.3% vs 15.4% (+1.9%, -16.1,15.5, p=0.984), TAR180 mg/dL decreased 20.5% vs 17.9% (-2.6%, -21.5,10.5, p=0.756), TAR250 mg/dL decreased 17.1% vs 6.0% (-11.1%. -20.3,2.7, p=0.375), TBR changed 0.41% vs -0.88% (+0.47, -0.16,1.37, p=0.054), DAT vs. SoC, respectively. Fitness tests, completed by 60% of participants, showed improvements in medium strength (bicep curls g=0.90 /p=0.06, chair stands g=0.63/p=0.18), daily physical function (g=0.56/p=0.20), aerobic performance (6min walk test g=0.24/p=0.61), agility/flexibility (timed up and go g=-0.30/p=0.49, back stretch g=-0.51/p=0.26). Conclusions: T2D patients managed by DAT had non-significant improvement in glucose control driven by decreased hyperglycemia 250 mg/dl. Non-significant modest increase in PA observed. Disclosure F. Sotomayor: None. C. Gothong: None. R. Hernandez: None. M.Y. Choe: None. G.I. Ash: None. W.H. Scott: None. L. Pinault: None. F. Gomez-Peralta: Advisory Panel; Abbott. Speaker's Bureau; Abbott. Advisory Panel; Eli Lilly and Company. Speaker's Bureau; Eli Lilly and Company. Advisory Panel; Insulcloud S.L. Speaker's Bureau; Medtronic. Advisory Panel; Novo Nordisk. Speaker's Bureau; Novo Nordisk. Advisory Panel; Sanofi. L.G. Singh: None. J.D. Sorkin: None. I. Spanakis: Research Support; Dexcom, Inc., Tandem Diabetes Care, Inc.
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Sotomayor et al. (Fri,) studied this question.
synapsesocial.com/papers/68e64d6bb6db6435875ddf18 — DOI: https://doi.org/10.2337/db24-1113-p
Fiorella Sotomayor
University of Maryland, Baltimore
CHIKARA GOTHONG
R. Cuenca Hernández
University of Maryland, Baltimore
Diabetes
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