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The Hispanic/Latino (H/La) population in the US experiences a notably high incidence of hypertension. Recent epidemiological findings reveal that more than 50% of H/La men over the age of 20 years suffer from high blood pressure. Even among adolescents aged 8 to 17 years, H/La youth exhibit the highest prevalence of hypertension compared to other racial groups. This significantly elevates the risk of cardiovascular diseases across the lifespan of this population. H/La is the largest ethnic minority in the US, constituting 19.1% of the current population, and is projected to make up 1/3rd of the US population by 2050. As such, it is crucial to study the potential mechanism responsible for the health disparities in this population. In this study, we investigated the cardiac autonomic function by assessing the baroreflex sensitivity (BRS) and heart rate variability (HRV) in young, healthy H/La and non-Hispanic white (NHW) individuals. We hypothesized that the cardiac autonomic function (BRS and HRV) will be impaired in young healthy H/La as compared to the healthy NHW adults. Ten minutes of resting beat-to-beat blood pressure (BP; finger plethysmography) and heart rate (ECG) were measured in 14 young healthy H/La adults (11 men, 3 women) and 14 age-, sex- and weight-matched NHW adults [age (H/La: 20 ± 2yr; NHW: 22 ± 4yr; mean ± SD, p=0.32); BMI (H/La: 24 ± 2 kg/m 2 ; NHW: 24 ± 2 kg/m 2 ; p = 0.92); positive family history of hypertension (H/La: 21.4%; NHW: 21.4%). The resting heart rate (H/La = 59 ± 5 bpm; NHW = 55 ± 6 bpm; p = 0.12), systolic BP (H/La = 107 ± 6 mmHg; NHW = 111 ± 6 mmHg; p = 0.14) and diastolic BP (H/La = 61 ± 5 mmHg; NHW = 63 ± 6 mmHg; p = 0.46) were similar in both the groups. The respiratory rate (H/La = 14 ± 3 bpm; NHW = 14 ± 3 bpm; p = 0.41) and the sample data used (H/La = 591 ± 59 beats; NHW = 554 ± 63 beats; p = 0.12) for both the populations were similar. We found that BRS (overall gain; H/La = 24 ± 6 ms/mmHg; NHW = 27 ± 10 ms/mmHg; p = 0.39) and heart rate variability (root mean square of successive differences between normal heart beats; RMSSD, H/La = 82 ± 29 ms; NHW = 102 ± 48 ms; p = 0.101) were not significantly different between the two groups. These data suggest that baroreflex sensitivity and heart rate variability are not different between young, healthy H/La and NHW adults. Supported by Kinesiology and Health Education UT Austin Start-up Account 19-2635-91. This is the full abstract presented at the American Physiology Summit 2024 meeting and is only available in HTML format. There are no additional versions or additional content available for this abstract. Physiology was not involved in the peer review process.
Dalve et al. (Wed,) studied this question.