Mp71-17 10-Year Trends in Perioperative Outcomes in Bladder Cancer Patients Undergoing Radical Cystectomy With Ileal Conduit Urinary Diversion

You have accessJournal of UrologyBladder Cancer: Non-invasive IV (MP71)1 May 2024MP71-17 10-YEAR TRENDS IN PERIOPERATIVE OUTCOMES IN BLADDER CANCER PATIENTS UNDERGOING RADICAL CYSTECTOMY WITH ILEAL CONDUIT URINARY DIVERSION Kevin L. Xu, Grace Ryu, Seyma Demirsoy, Elizaveta Makarova, Katrina Bakhl, Suzanne Boltz, Roderick K. Clark, Alireza Aminsharifi, Matthew Kaag, Jay D. Raman, Tullika Garg, and Hong Truong Kevin L. XuKevin L. Xu , Grace RyuGrace Ryu , Seyma DemirsoySeyma Demirsoy , Elizaveta MakarovaElizaveta Makarova , Katrina BakhlKatrina Bakhl , Suzanne BoltzSuzanne Boltz , Roderick K. ClarkRoderick K. Clark , Alireza AminsharifiAlireza Aminsharifi , Matthew KaagMatthew Kaag , Jay D. RamanJay D. Raman , Tullika GargTullika Garg , and Hong TruongHong Truong View All Author Informationhttps://doi.org/10.1097/01.JU.0001009548.76580.ba.17AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Radical cystectomy (RC) is associated with considerable postoperative morbidities. Enhanced recovery after surgery protocol is a multimodal pathway implemented to improve postoperative outcomes over the past decade. We compared the 30- and 90-day postoperative morbidity and mortality rates following RC and ileal conduit urinary diversion (RC/IC) between 2012-2017 and 2017-2022 to evaluate trends in patient outcomes and areas for improvement. METHODS: This retrospective cohort study used data from TriNetX US Collaborative network to access de-identified patient health records across healthcare organizations (HCOs). We used ICD-10 codes to identify bladder cancer patients who underwent RC/IC and postoperative complications from 01/01/2012 to 01/01/2022. We compared the 30 and 90-day postoperative morbidity and mortality rates between 2012-2017 and 2017-2022 using the chi-squared test. RESULTS: Demographics are summarized in Table 1. 40 HCOs reported 5,386 cases in 2012-2017, and 43 HCOs reported 7,684 cases in 2017-2022. Mean age was 68.4±10.4 years; 75% were male; 82% were white. 30 and 90-day complications by five-year period were summarized in Table 2. Overall all-cause mortality at 30 and 90-days postop were 2.1% and 4.9%, respectively, and remain unchanged over the past decade. The most common complications within 90-days of surgery were acute kidney injury (19.7%), urosepsis (18.9%), and UTI (15.0%). While infectious complications improved over the past five years, renal function and gastrointestinal complications such as small bowel obstruction increased. CONCLUSIONS: RC/IC is associated with high perioperative morbidities with up to 1 in 5 patients experiencing a complication within 90-days post-surgery. Despite refinements in clinical care pathways and emergence of minimally invasive approaches, the overall perioperative morbidity and mortality rates have not improved much over the past decade. Further research is needed to improve surgical outcomes for bladder cancer patients. Source of Funding: No external funding to report for this work © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e1167 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Kevin L. Xu More articles by this author Grace Ryu More articles by this author Seyma Demirsoy More articles by this author Elizaveta Makarova More articles by this author Katrina Bakhl More articles by this author Suzanne Boltz More articles by this author Roderick K. Clark More articles by this author Alireza Aminsharifi More articles by this author Matthew Kaag More articles by this author Jay D. Raman More articles by this author Tullika Garg More articles by this author Hong Truong More articles by this author Expand All Advertisement PDF downloadLoading ...