Key points are not available for this paper at this time.
No AccessJournal of UrologyAdult Urology11 Apr 2024Bladder Cancer Survivors Who Do Not Smoke Have Better Longitudinal Health Related Quality of Life Measures: An Assessment of the Comparative Effectiveness of Survivorship Health in Bladder Cancer (CEASE-BC) Study Hannah Kay, Sarah N. Silver, Angela B. Smith, Ramsankar Basak, Kimberly Shoenbill, Deborah Usinger, Adam O. Goldstein, Richard S. Matulewicz, Ronald Chen, and Marc A. Bjurlin Hannah KayHannah Kay , Sarah N. SilverSarah N. Silver , Angela B. SmithAngela B. Smith , Ramsankar BasakRamsankar Basak , Kimberly ShoenbillKimberly Shoenbill , Deborah UsingerDeborah Usinger , Adam O. GoldsteinAdam O. Goldstein , Richard S. MatulewiczRichard S. Matulewicz , Ronald ChenRonald Chen , and Marc A. BjurlinMarc A. Bjurlin Corresponding Author: Marc A. Bjurlin, Associate Professor, Department of Urology, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, 101 Manning Drive, 2nd floor, Chapel Hill, NC ( (email protected) ). https://orcid.org/0000-0003-3500-8849 View All Author Informationhttps://doi.org/10.1097/JU.0000000000003964AboutPDF ToolsAdd to favoritesDownload CitationsTrack Citations ShareFacebookLinked InTwitterEmail Abstract Purpose: Cigarette smoking is the most common risk factor for the development of bladder cancer (BC), yet there is a paucity of data characterizing the relationship between smoking status and longitudinal Health Related Quality of Life (HRQoL) outcomes in patients with BC. We examined the association between smoking status and HRQoL among patients with BC. Materials and Methods: Data was sourced from a prospective, longitudinal study open between 2014 and 2017, which examined HRQoL in patients aged ≥ 18 years diagnosed with BC across North Carolina. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire core instrument (QLQ-C30) was administered at 3, 12, and 24 months after BC diagnosis. Our primary exposure of interest was current smoking status. Linear regression using Generalized Estimating Equations was used to analyze the relationship between smoking status and various domains of the QLQ-C30. Results: A total of 154 patients enrolled in the study. Eighteen percent were classified as smoking at 3 months from diagnosis, packs per day (PPD) ranged from < 0.5 to 2. When controlling for time from diagnosis, demographic covariates, cancer stage, and treatment type, mean differences (MD) for physical function (7.4), emotional function (5.6), and fatigue measures (−8.2) were significantly better for patients with BC who did not smoke. Conclusions: Patients with BC who do not smoke have significantly better HRQoL scores in the domains of physical function, emotional function, and fatigue. These results underscore the need to treat smoking as an essential component of BC care. © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Supplementary Materials Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Keywordsbladder cancersmokingtobaccoquality of lifeMetrics Author Information Hannah Kay More articles by this author Sarah N. Silver More articles by this author Angela B. Smith More articles by this author Ramsankar Basak More articles by this author Kimberly Shoenbill More articles by this author Deborah Usinger More articles by this author Adam O. Goldstein More articles by this author Richard S. Matulewicz More articles by this author Ronald Chen More articles by this author Marc A. Bjurlin Corresponding Author: Marc A. Bjurlin, Associate Professor, Department of Urology, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, 101 Manning Drive, 2nd floor, Chapel Hill, NC ( (email protected) ). More articles by this author Expand All Advertisement PDF downloadLoading ...
Kay et al. (Thu,) studied this question.