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April 2, 2016New England Journal of Medicine5,089 citationsOpen Access

Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients

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MLMartin B. LeonCSCraig R. SmithMMMichael J. Mack

Key Result

In intermediate-risk patients, transcatheter aortic valve replacement (TAVR) had outcomes similar to surgical aortic valve replacement regarding death or disabling stroke.

Structured PICO

Does transcatheter aortic-valve replacement (TAVR) reduce death or disabling stroke in intermediate-risk patients compared to surgical aortic-valve replacement?

P
Population
Intermediate-risk patients requiring aortic-valve replacement
I
Intervention
Transcatheter aortic-valve replacement (TAVR)
C
Comparator
Surgical aortic-valve replacement
O
Outcome
Composite of death or disabling strokecomposite

In intermediate-risk patients, TAVR provides similar outcomes to surgical aortic-valve replacement for the composite of death or disabling stroke.

Abstract

In intermediate-risk patients, TAVR was similar to surgical aortic-valve replacement with respect to the primary end point of death or disabling stroke. (Funded by Edwards Lifesciences; PARTNER 2 ClinicalTrials.gov number, NCT01314313.).

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Cite This Study

Leon et al. (2016) studied this question. In intermediate-risk patients, transcatheter aortic valve replacement (TAVR) had outcomes similar to surgical aortic valve replacement regarding death or disabling stroke.

synapsesocial.com/papers/69615ed33b3c6cd0a4920d12https://doi.org/10.1056/nejmoa1514616
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