Actuality. Effective oral hygiene products with an anti-plaque effect can significantly reduce the risk of developing diseases. New active ingredients of oral hygiene products, such as octacalcium phosphate, nanohydroxyapatite, aminophthroid, as well as various plant extracts and probiotics, are becoming increasingly popular due to their unique properties that help not only in the fight against plaque, but also in maintaining the health of hard and soft tissues of the mouth. Material and methods. To study the preventive effect of "PRESIDENT® Profi Biomineral" toothpaste, a clinical trial was conducted with the participation of 60 people (34 women, 26 men). The study participants used the preventive toothpaste "PRESIDENT® Profi Biomineral" every day, morning and evening, for 28 days. An objective assessment of the condition of the hard tissues of the mouth was carried out every week in order to determine the anti-caries, remineralizing and desensitizing effects, as well as an assessment of the buffer capacity of saliva. Results. Based on the results of a study of the preventive effect of oral hygiene products based on octacalcium phosphate in the examined patients who used PRESIDENT® Profi Biomineral toothpaste for individual oral hygiene, it was determined that the anti-caries effectiveness increased from 2.03 ± 0.90% to 16.24 ± 4.34% in one month of using PRESIDENT® Profi Biomineral paste. The remineralizing efficacy in one month of using PRESIDENT® Profi Biomineral toothpaste was 24.76 ± 3.92%. The desensitive efficiency increased from 7.11 ± 1.23% to 19.72 ± 5.24% and increased by 12.61%. Conclusion. It was revealed that the toothpaste "PRESIDENT® Profi Biomineral" based on octacalcium phosphate, when used in individual hygiene measures, has a significant preventive effect, which was established as a result of its clinical testing.
Ulitovskiy et al. (Fri,) studied this question.