What question did this study set out to answer?

This study investigates the clinical features and laparoscopic treatment outcomes for ovarian pregnancy.

February 2, 2026Clinical and Experimental Obstetrics & Gynecology0 citationsOpen Access

Laparoscopic Treatment of Ovarian Pregnancy: A Series of 16 Consecutive Cases

LXLuxi XiaFirst Affiliated Hospital Zhejiang University TQTongyun QiWomen's Hospital LCLimeng CaiNortheast Agricultural University

Key Points

This study investigates the clinical features and laparoscopic treatment outcomes for ovarian pregnancy.
Retrospective analysis of 16 consecutive cases of ovarian pregnancy treated surgically.
Data collection included sociodemographic details, symptoms, risk factors, and diagnostic tests.
Outcomes were assessed based on operative times, hospital stays, and complications.
Mean age of patients was 32.44 years, with a mean gestational age of 50.13 days at diagnosis.
Abdominal pain was the most common symptom, affecting 93.75% of patients.
The median serum β-hCG was 4756.03 mIU/mL, with a range of 700.56 to 12,661.89 mIU/mL.
Ruptured ovarian pregnancies occurred in 81.25% of cases, with hemoperitoneum volumes averaging 900 mL.
No patients needed further treatment after laparoscopic surgery.

Abstract

Background: Ovarian pregnancy (OP) is a rare type of ectopic pregnancy (EP) that can become life-threatening due to the risk of severe complications, such as pelvic hemorrhage and circulatory collapse. The diagnosis and treatment of OP are challenging. Thus, this study aimed to investigate the clinical characteristics of OP, explore current and potential diagnostic and therapeutic strategies, and summarize the experience with laparoscopic treatment for OP. Methods: A retrospective analysis was performed on data from 16 consecutive patients with OP who underwent surgical treatment between March 2016 and May 2025. We collected clinical data from these patients, including sociodemographic information, suspected risk factors, clinical manifestations, preoperative examinations e.g., serum beta human chorionic gonadotropin (β-hCG) test and ultrasonography, treatment methods, and outcomes. Results: The mean age of the patients was 32.44 ± 6.37 years, and the mean gestational age at diagnosis was 50.13 ± 9.91 days. Abdominal pain was the most common presenting symptom (reported in 15 patients, 93.75%), followed by vaginal bleeding (7 patients, 43.75%) and hemorrhagic shock (2 patients, 12.50%). Serum β-hCG (measured in 15 patients) ranged from 700.56 to 12,661.89 mIU/mL, with a median of 4756.03 mIU/mL interquartile range (IQR), 1730.39–8174.70 mIU/mL. The preoperative ultrasound diagnostic rate for OP was 6.25% (1/16). All patients underwent laparoscopic surgery for the excision of OP tissue. A ruptured OP was observed in 13 patients (81.25%). Hemoperitoneum ranged from 30 to 2000 mL, with a median of 900 mL (IQR, 350–1000 mL). The mean operative time was 1.23 ± 0.60 h, and the mean postoperative hospital stay was 2.50 ± 1.51 days. None of the patients required additional surgical or medical treatments after laparoscopy (LC). Conclusions: Rupturing is a common complication of OP, highlighting the importance of early diagnosis and timely intervention. Laparoscopic techniques facilitate the early detection and accurate diagnosis of OP. Laparoscopic surgery is a safe, effective, and minimally invasive treatment option for OP.

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