Oxygen carriers: core strategies for modulating hypoxic microenvironments and promoting healing in chronic wounds

Key Points

• The review aims to summarize and evaluate oxygen carriers used in chronic wound therapy.
• Summarizes oxygen carriers based on perfluorocarbons and hemoglobin.
• Compares oxygen delivery capacities of these carriers.
• Analyzes synergistic biological effects on wound healing.
• Describes challenges in clinical translation.
• Identifies differences in O2 delivery capacities among various carriers.
• Highlights potential synergistic effects that may enhance healing.
• Discusses significant challenges hindering effective clinical applications.