Supramolecular Net-Suppressor drives tumor vascular-immune microenvironment remodeling with spatiotemporal synchronization for Renal Cancer Therapy

Key Points

• This research aims to explore how the supramolecular net-suppressor can enhance therapy effectiveness by remodeling the tumor vascular-immune microenvironment in renal cancer.
• Developed a supramolecular net-suppressor for cancer therapy.
• Investigated its effects on tumor microenvironment dynamics.
• Evaluated spatiotemporal synchronization of therapeutic agents.
• The supramolecular net-suppressor significantly remodels the tumor microenvironment.
• It enhances the effectiveness of anti-angiogenic agents and immune checkpoint inhibitors.
• Observed improved coordination of immune and vascular responses in treatment.