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A double helix twist in HIV vaccine design | Synapse

February 8, 2026Science0 citations

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A double helix twist in HIV vaccine design

OBOliver BannardJohn Radcliffe Hospital MHMark HowarthUniversity of Cambridge

Key Points

To explore how DNA origami scaffolds can improve antibody responses to HIV antigens.
Used DNA origami to create scaffolds that display HIV antigens.
Administered the scaffolds to mice.
Measured the resulting antibody responses.
Mice showed focused antibody responses targeting HIV antigens.
The DNA origami scaffolds effectively enhanced immune reaction.

Abstract

DNA origami scaffolds displaying HIV antigens stimulate focused antibody responses in mice

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Cite This Study

Bannard et al. (Thu,) studied this question.

synapsesocial.com/papers/6988291e0fc35cd7a8849348 https://doi.org/https://doi.org/10.1126/science.aee5778