CT-derived visceral and intramuscular adipose tissue were associated with lipid plaque formation and vascular inflammation, while higher muscle mass protected against calcified plaque progression.
Observational
Are CT-derived body composition metrics associated with coronary plaque components and vascular inflammation?
CT-derived body composition metrics have divergent effects on coronary plaque components, highlighting the potential value of precise body composition analysis in cardiovascular risk assessment.
Different body composition metrics exert divergent effects on various components of coronary plaque. Our study suggests that VAT and IMAT may contribute to lipid plaque formation, potentially mediated by a state of increased vascular inflammation as captured by FAI, while a higher muscle mass may protect against the progression of calcified plaque. These findings highlights the necessity of precise body composition analysis in cardiovascular risk assessment.
Gao et al. (Sun,) conducted a observational in Coronary plaque and vascular inflammation. CT-derived body composition metrics (VAT, IMAT, muscle mass) was evaluated on Coronary plaque components and vascular inflammation. CT-derived visceral and intramuscular adipose tissue were associated with lipid plaque formation and vascular inflammation, while higher muscle mass protected against calcified plaque progression.