From technological iteration to clinical breakthrough: advances of CAR-T cell therapy in autoimmune diseases

Key Points

• The aim is to explore the advancements of CAR-T cell therapy for treating autoimmune diseases (AIDs).
• Review of current CAR-T cell therapy technologies and their applications in AIDs.
• Analysis of challenges faced in clinical trials and treatment.
• Discussion of potential strategies to enhance clinical translation.
• CAR-T cell therapy shows promise in managing refractory autoimmune diseases.
• Addressing existing challenges could enhance its effectiveness and increase clinical application.
• Current advancements highlight the innovative potential of CAR-T therapy in diverse autoimmune contexts.