What question did this study set out to answer?

The study aims to explore the genome sequences of two Syntrophomonas strains that degrade short-chain fatty acids.

February 14, 2026Open Access

Genomes of Syntrophomonas erecta GB4-38 T and Syntrophomonas erecta subsp. sporosyntropha 5-3-Z T that degrade C4-8 short-chain fatty acids

SHSung Min Ha EHEthan HummUniversity of California, Los Angeles NWNeil Q. WoffordUniversity of Oklahoma

Key Points

The study aims to explore the genome sequences of two Syntrophomonas strains that degrade short-chain fatty acids.
Obtained genome sequences of Syntrophomonas erecta GB4-38 T and Syntrophomonas erecta subsp. sporosyntropha 5-3-Z T
Examined their metabolic pathways related to short-chain fatty acid degradation
Utilized co-culture techniques with hydrogen-consuming strains
Successfully sequenced the genomes of both Syntrophomonas strains
Identified key genes associated with the degradation of C4-C8 short-chain fatty acids
Confirmed effective hydrogen consumption when grown in co-culture

Abstract

ABSTRACT We report the genome sequences of two syntrophic gram-negative bacteria, Syntrophomonas erecta GB4-38 T and Syntrophomonas erecta subsp. sporosyntropha 5-3-Z T , which degrade C4-C8 short-chain fatty acids when grown in co-culture with a suitable hydrogen-consuming microbial strain.

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