Rational design of a chitosan-coated cobalt ferrite nanozyme coupled with molecularly imprinted polymer for trace analysis of Buspirone in complex matrices: application to spiked human plasma and environmental water samples

Key Points

• To develop a sensitive sensor for detecting Buspirone in complex samples using innovative materials.
• Integrated a polydopamine molecularly imprinted polymer onto chitosan-coated cobalt ferrite.
• Utilized colorimetric analysis for detection of Buspirone.
• Tested on spiked human plasma and environmental water samples.
• Achieved high sensitivity and selectivity for Buspirone detection.
• Successfully detected Buspirone in both human plasma and water samples with good accuracy.