The Age at Onset of LRRK2 p.Gly2019Ser Parkinson's Disease Across Ancestries and Countries of Origin.

Key Points

• The research aims to investigate how genetic ancestry and country of origin affect the age at onset of LRRK2-related Parkinson's disease.
• Analyzed genetic data from diverse populations
• Compared age at onset among different ancestral groups
• Examined environmental factors correlating with age at onset
• Identified variations in age at onset across different ancestries
• Showed a significant association between country of origin and age at onset
• Highlighted the role of both genetic and environmental influences on disease onset