Severity of surgical histopathological fibrosis predicted postoperative recurrence in Crohn’s disease: a multi-center retrospective cohort study

Key Points

• The study aims to assess how the severity of intestinal fibrosis affects the risk of recurrence after surgery in Crohn’s disease.
• Conducted a multi-center retrospective cohort study
• Evaluated histopathological fibrosis at lesion sites and resection margins
• Analyzed postoperative clinical and endoscopic recurrence rates
• Increased severity of intestinal fibrosis correlated with higher postoperative recurrence rates
• Both lesion site and resection margin fibrosis independently predicted recurrence
• Histopathological assessment may aid in identifying high-risk patients

Abstract