What does this research mean for the field?

Some nutritional supplements exhibit relatively higher periodontal health benefits compared to others. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This research aims to evaluate the effectiveness of nutritional supplements in improving periodontal health, both alone and alongside nonsurgical periodontal therapy.

March 1, 2026Open Access

Effects of Nutritional Supplements Alone or as an Adjunct to Nonsurgical Periodontal Therapy: A Systematic Review and Network Meta-Analysis.

Key Points

This research aims to evaluate the effectiveness of nutritional supplements in improving periodontal health, both alone and alongside nonsurgical periodontal therapy.
Conducted a systematic review of existing studies on nutritional supplements and periodontal therapy.
Utilized network meta-analysis to compare various nutritional supplements.
Identified seven types of nutritional supplements and assessed their health benefits.
Some nutritional supplements show higher benefits for periodontal health than others.
Evidence on the effectiveness of supplements as an adjunct to nonsurgical therapy is limited and suggests further research is necessary.

Abstract

Among the seven types of NSs identified in this NMA, some NSs exhibit relatively higher periodontal health benefits. However, evidence regarding the effectiveness of NSs as an adjunct to NSPT is still insufficient and warrants further high-quality clinical trials.

Effects of Nutritional Supplements Alone or as an Adjunct to Nonsurgical Periodontal Therapy: A Systematic Review and Network Meta-Analysis.

Key Points

Abstract

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