Integrated Bioinformatics Analysis of a TF-miRNA-mRNA Regulatory Network in Retinal Vein Occlusion with Metabolic Syndrome and its Association with Clinical Predictors.

Key Points

• This research aims to explore a regulatory network involving transcription factors, miRNAs, and mRNAs linked to retinal vein occlusion and metabolic syndrome.
• Integrated bioinformatics approach
• Analysis of TF-miRNA-mRNA interactions
• Identification of potential biomarkers from clinical data
• Focus on ABCA1 and hsa-miR-192-5p
• Identification of TF-miRNA-mRNA network associated with RVO-MetS
• ABCA1 and hsa-miR-192-5p suggested as potential biomarkers
• Findings support existing clinical predictors despite small sample size