What does this research mean for the field?

Orthostatic blood pressure changes are significantly influenced by socio-demographic, anthropometric, and biophysical factors among adults in Ekiti State, Nigeria. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The research aims to explore how socio-demographic, anthropometric, and biophysical factors affect orthostatic blood pressure changes among adults.

March 1, 2026Open Access

Orthostatic blood pressure changes among adults in Ekiti state, Nigeria: Impact of socio-demographic, anthropometric, and biophysical factors.

Key Result

Systolic BP decreased by 4% after 1-min standing; orthostatic MAP at 1,3,5 min correlated negatively with height and positively with BMI, hip, waist circumference (p<0.05).

Key Points

The research aims to explore how socio-demographic, anthropometric, and biophysical factors affect orthostatic blood pressure changes among adults.
Assessed orthostatic blood pressure changes in 140 adults in Ekiti State.
Collected socio-demographic and anthropometric data using standardized tools.
Conducted blood pressure measurements at baseline, standing, and sitting positions.
Systolic blood pressure decreased by 4% after 1 minute of standing.
Diastolic blood pressure increased by 6.1% at 3 minutes and 4.8% at 5 minutes compared to baseline.
Mean arterial pressure correlated positively with occupation and education level, and negatively with height.

Structured PICO

How do socio-demographic, anthropometric, and biophysical factors impact orthostatic blood pressure changes among adults?

Population

140 adults (age range: 18-70 years, 28% male, 72% female) living in Ekiti State, Nigeria.

Intervention

Postural change (standing from baseline)

Comparator

Baseline (pre-standing)

Outcome

Orthostatic blood pressure changes (systolic and diastolic) at 1, 3, and 5 minutes of standingsurrogate

Orthostatic blood pressure responses vary significantly with postural changes and are influenced by body composition and lifestyle factors such as BMI, waist circumference, and occupation.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Orthostatic intolerance is the inability to maintain upright posture, a key manifestation of autonomic dysfunction that can lead to orthostatic hypotension (OH). We aimed to investigate orthostatic blood pressure (BP) changes among cohorts living in Ekiti State and to explore plausible underlying factors. We encompassed 140 participants (28% male; 72% female; age range: 18-70 years) in our preliminary study. Socio-demographic and anthropometric indices were collected using appropriate tools. Orthostatic responses were assessed at baseline, standing, and sitting following standardized protocols. Systolic (BP) decreased significantly by 4% after 1-min standing (130 ± 22 mmHg) compared to baseline (137 ± 20 mmHg). Diastolic (BP) increased significantly by 6.1% at 3 min (87 ± 13 mmHg) and 4.8% at 5 min (86 ± 12 mmHg) compared to baseline (82 ± 11 mmHg) (p < 0.001). Occupation (traders) and education level (secondary) are positively associated with mean arterial pressure (MAP) at 1- and 3-min standing times (p < 0.05). Orthostatic MAP at 1, 3, and 5 min correlated negatively with height but positively with body mass index (BMI), hip, and waist circumference (p < 0.05). These preliminary findings suggest a potential role for body composition and lifestyle in regulating autonomic cardiovascular function in response to postural changes.