O balão WAVE com três ciclos de insuflação aumentou o número total de fragmentos para 112,6 versus 48,6 com balão padrão de insuflação única e reduziu grandes fragmentos >9 mm para 7,6 versus 13,2 (p < 0,001).
Outro
O conceito WAVE aumenta a fragmentação e reduz grandes fragmentos em um modelo in vitro de estenose arterial calcificada em comparação com a PTA padrão?
The WAVE balloon concept with multiple shifted inflations significantly increases fragmentation and reduces large fragments in an in vitro calcified stenosis model, suggesting potential for improved angioplasty outcomes.
Effect estimate: p < 0.001 (95% CI 112.6 (95% CI [103.3, 121.9]) fragments vs. 48.6 (95% CI [42.5, 54.7]) fragments; fragments >9mm: 7.6 (95% CI [6.4, 8.8]) vs. 13.2 (95% CI [11.6, 14.8]))
Absolute Event Rate: 112.6% vs 48.6%
p-value: p=<0.001
O conceito WAVE cria fragmentos mais numerosos e menores em um modelo arterial calcificado abaixo do joelho in vitro. Esses achados mostram um potencial promissor para melhorar os resultados de futuros procedimentos de angioplastia.
Binkert et al. (2026) studied Calcified arterial lesions in below-the-knee (BTK) arteries modeled in vitro. WAVE balloon with three inflation cycles and slight balloon shift after each inflation (WAVE concept) vs. Standard angioplasty balloon with single inflation cycle (standard PTA) was evaluated on Total number of fragments and number of fragments exceeding 9 mm in length generated by balloon angioplasty (p < 0.001, 95% CI 112.6 (95% CI [103.3, 121.9]) fragments vs. 48.6 (95% CI [42.5, 54.7]) fragments; fragments >9mm: 7.6 (95% CI [6.4, 8.8]) vs. 13.2 (95% CI [11.6, 14.8]), p=<0.001). The WAVE balloon with three inflation cycles increased total number of fragments to 112.6 versus 48.6 with standard balloon single inflation and reduced large fragments >9 mm to 7.6 versus 13.2 (p < 0.001).