Expanding the Morphological, Immunohistochemical, and Molecular Spectrums of NUT Carcinoma at Rare Sites of Head and Neck Region.

Key Points

• The study aims to enhance understanding of NUT carcinoma's characteristics in rare head and neck sites.
• Analyzed cases of NUT carcinoma from diverse head and neck locations.
• Assessed morphological and immunohistochemical features.
• Reviewed clinical outcomes and prognosis.
• Found that HN-NCs have a poor prognosis, particularly those from the oral mucosa.
• Highlighted the importance of including HN-NC in differential diagnoses of undifferentiated malignancies.