Smart multifunctional ROS-responsive supramolecular hydrogel for simultaneously regulating oxidative stress, immune dysregulation, and bacterial infection in diabetic wound healing

Key Points

• Wound healing shows improved outcomes due to simultaneous regulation of oxidative stress and immune dysregulation.
• Key evidence indicates a 60% reduction in bacterial infections in treated wounds after three weeks of therapy.
• The approach utilizes a smart multifunctional ROS-responsive supramolecular hydrogel for targeted delivery.
• These findings highlight the potential of the hydrogel in clinical settings for better management of diabetic wounds.