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Decoding the diabetes-pancreatic adenocarcinoma connection: the critical role of PILRA in intermediate monocyte activity | Synapse
March 3, 2026
Open Access
Decoding the diabetes-pancreatic adenocarcinoma connection: the critical role of PILRA in intermediate monocyte activity
YW
Yu Wen
Tongji Hospital
ZL
Zhenhua Liu
SZ
Shuaimin Zhang
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Key Points
PILRA significantly affects intermediate monocyte activity, influencing pancreatic adenocarcinoma development.
Intermediate monocyte activity increased by 40% in diabetic conditions, emphasizing the immune response.
Observational analysis of molecular interactions reveals how PILRA mediates immune functions linked to cancer.
Identifying the connection supports the potential for new treatment strategies targeting immune pathways in diabetes.
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Wen et al. (Sat,) studied this question.
synapsesocial.com/papers/69a759f4c6e9836116a1f5dc
https://doi.org/https://doi.org/10.1186/s12920-026-02310-z