Metagenomic next-generation sequencing for the diagnosis and evaluation of pediatric pleural effusion: a case series

Key Points

• Diagnosis of pediatric pleural effusion significantly improves using metagenomic next-generation sequencing, enabling better assessment of conditions.
• The series indicates that metagenomic analysis might uncover diverse microbial profiles in pleural effusions, aiding treatment decisions.
• Observational analysis of cases shows how effectively this method identifies pathogens and associated complications in children with pleural effusion.
• Findings suggest that this diagnostic advancement may enhance clinical outcomes, with further validation needed to generalize across populations.