A robust and interpretable predictive model was developed to estimate 5-year Ortho-K lens control efficacy using Δ1, Δ3, and flat E. The integrated SHAP analysis provided mechanistic insight and highlighted the clinical threshold (Δ3 = 0.05 mm) as a potential early warning indicator for suboptimal myopia control. The dynamic online nomogram enables individualized risk estimation and supports precision-guided intervention in pediatric myopia management.
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Frontiers in Cell and Developmental Biology
Huazhong University of Science and Technology
Tianjin Medical University
Tianjin Medical University Eye Hospital
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Wang et al. (Tue,) studied this question.