A lysosome-targeting near-infrared optical probe conferring polarity-induced azo-hydrazone coexistence for photothermal therapy

Key Points

• Photothermal therapy demonstrates effectiveness in targeted cells using a lysosome-targeting optical probe, enhancing treatment precision.
• Key evidence indicates notable coexistence of azo-hydrazone components, contributing to treatment efficacy and cellular uptake.
• Assessment using optical probes reveals polarity-induced mechanisms crucial for therapeutic effectiveness in cancer cells.
• This study highlights the potential for improved cancer therapies through lysosomal targeting and further investigation is warranted.