Neutralizing activity analysis of mimotopes against porcine epidemic diarrhea virus (PEDV) spike protein

Key Points

• Mimotopes showed notable neutralizing activity against the PEDV spike protein, indicating their potential as vaccine candidates.
• Analysis revealed that certain mimotopes significantly inhibited PEDV infection in vitro, highlighting their effectiveness.
• Assessment was conducted using a series of laboratory tests that measured the interactions between mimotopes and the spike protein.
• These findings may enable the development of effective vaccines, although further validation in animal models is needed.