Characteristics of humoral and T-cell immune responses in people living with HIV after breakthrough SARS-CoV-2 Omicron variant infection during December 2022 to January 2023

Key Points

• Humoral immune responses were observed in HIV individuals after Omicron infection, indicating adaptive immunity activation.
• During December 2022 to January 2023, a significant increase in T-cell responses was noted among the affected individuals.
• Observational analysis focused on breakthrough infections of the Omicron variant among people living with HIV.
• Highlighting the need for tailored vaccine strategies in vulnerable populations like those living with HIV.