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Social isolation and loneliness effects on medication adherence in older adults: perspectives from a systematic review | Synapse
March 3, 2026
Open Access
Social isolation and loneliness effects on medication adherence in older adults: perspectives from a systematic review
AI
A Improta
University of Rome Tor Vergata
ST
Sofia Taborri
University of Rome Tor Vergata
NG
Noemi Giannetta
Università Cattolica del Sacro Cuore
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Key Points
Medication adherence is significantly affected by social isolation in older adults, impacting health outcomes.
Older adults experiencing loneliness are less likely to follow prescribed medication regimens, which can lead to adverse effects.
Systematic review across various studies illustrates the connection between loneliness, social isolation, and adherence.
Efforts to improve social interactions among older adults may enhance medication adherence and overall health.
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Improta et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75c21c6e9836116a24a32
https://doi.org/https://doi.org/10.1186/s12889-025-26085-7