Expression profile of circular RNAs in type 2 diabetes mellitus patients with retinopathy

Key Points

• Downregulated circRNAs were identified, particularly hsa_circRNA_407262, which may indicate a pivotal role in the development of diabetic retinopathy.
• Three specific circRNAs were found to be upregulated, shedding light on the potential molecular pathways involved.
• The assessment involves a comprehensive profiling of circRNAs in type 2 diabetes patients with diabetic retinopathy.
• Findings may prompt further investigation into circRNAs as viable biomarkers for early diagnosis of diabetic retinopathy.

Abstract