Type 2 diabetes mellitus is associated with specific temporal and functional abnormalities in default mode network connectivity that correlate with disease duration.
These findings indicate that T2DM duration correlates with reduced highly efficient DMN connectivity, and that the BF may regulate cognitive function via the dMPFC subsystem. The results reveal temporal and functional specificity in abnormal DMN connectivity in patients with T2DM and enrich the neural atlas of DMN dysfunction in this population.
Zhang et al. (Wed,) studied this question.