The triglyceride-glucose index in relation to psychotic symptoms in adolescents with major depressive disorder

Key Points

• Psychotic symptoms increased with triglyceride-glucose index, showing a J-shaped curve relationship.
• A threshold value around 8.06 in the TyG index appears critical for symptom exacerbation.
• Analysis based on a dose-response relationship was conducted with adolescents diagnosed with major depressive disorder.
• This finding underscores the potential for metabolic factors in understanding psychosis in depressive disorders.