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Anti-LGI-1 autoimmune encephalitis: Insights from literature and a very late-onset case report | Synapse
March 3, 2026
Anti-LGI-1 autoimmune encephalitis: Insights from literature and a very late-onset case report
CS
Cansu Sarıkaya
Bahçeşehir University
BG
Bengül Fatma Gölge
CB
Canan Aykut Bingöl
Yeditepe University
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Key Points
Autoimmune encephalitis presents significant neurological symptoms, especially in late-onset cases.
An 85-year-old patient exhibited anti-LGI-1 antibodies, indicating a rare manifestation of the disease.
Literature review provides context on how late-onset cases can differ from classic presentations.
Understanding late-onset autoimmune encephalitis may enhance diagnosis and treatment outcomes.
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Sarıkaya et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75d23c6e9836116a26aee
https://doi.org/https://doi.org/10.1016/j.clineuro.2026.109336