The incidence of chronic drug-induced liver injury: a systematic review and meta-analysis

Key Points

• Chronic drug-induced liver injury incidence significantly varies, indicating substantial clinical concern for liver health.
• Meta-analysis revealed that the incidence rate for chronic liver injury caused by drugs is estimated at 14.5 per 100,000 individuals.
• Systematic review across multiple studies identified various drug classes associated with liver injury, emphasizing the need for further surveillance.
• Highlighting the potential public health impact, understanding drug-induced liver injury can inform safer prescribing practices.