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Coordinating mRNA maturation: The U1 relay model | Synapse
March 3, 2026
Coordinating mRNA maturation: The U1 relay model
YY
Yoseop Yoon
University of California, Irvine
CQ
Chang Quan
LS
Lindsey Soles
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Key Points
The U1 relay model coordinates mRNA maturation with gene expression processes, enhancing understanding of RNA processing.
Key evidence shows that U1 snRNP directly influences spliceosome assembly, potentially altering gene regulation.
Analysis of RNA processing mechanisms illustrates the central role of U1 in mRNA maturation through dynamic interactions.
Implications suggest future studies should consider the U1 relay model's impact on gene expression, especially under stress.
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Yoon et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75d44c6e9836116a2700c
https://doi.org/https://doi.org/10.1016/j.molcel.2026.01.006