Multicomponent reactions with Meldrum's acid and isocyanides as a valuable synthetic approach: An update

Key Points

• Multicomponent reactions utilizing meldrum's acid result in diverse synthetic outcomes, showcasing their versatility.
• Enhanced reactivity of isocyanides provides a pathway for creating complex molecular architectures efficiently.
• Assessment of existing synthetic strategies reveals the increasing importance of catalysts in optimizing reaction conditions.
• The findings imply that further exploration of these reactions could lead to innovative applications in drug development.