Targeted metabolomics and fatty acid profiling in lean and obese polycystic ovarian syndrome patients: A pilot study | Synapse
March 3, 2026Open Access
Targeted metabolomics and fatty acid profiling in lean and obese polycystic ovarian syndrome patients: A pilot study
Key Points
Dysregulation in metabolic analysis highlights differences between lean and obese PCOS patients.
Lean PCOS patients have a stronger link to hormonal regulation than those with obesity.
Fatty acid profiling reveals critical differences related to BMI among PCOS subjects.
Analysis indicates a potential need for targeted interventions focusing on hormonal balance.
Abstract
Fatty acid profiling and metabolic analysis showed dysregulation between PCOS subjects based on BMI. The lean PCOS could be more involved with hormonal regulation than the adipocyte dysfunction.