March 3, 2026Open Access

Introduction to animal modelling: factors and tools for choosing the optimal model for sarcoma research—a comprehensive literature review

Key Points

Accurate model selection enhances understanding of tumour behaviour and therapeutic responses in sarcoma.
A practical guide discusses various model classes and inoculation routes for optimal outcomes.
Comprehensive literature review highlights specific use cases and endpoints for sarcoma research.
Active repositories and databases are listed to aid in finding suitable animal models for ongoing studies.

Abstract

With the right model, researchers can accurately study tumour behaviour, therapeutic responses and the basic mechanisms that underlie sarcoma development. We provide a practical guide for animal model selection though detailed discussion of model classes, inoculation routes, and endpoint to sarcoma-specific use cases as well as a list of active repositories/databases.

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Discussion

Cite this study

Remiszewski et al. (Thu,) studied this question.

synapsesocial.com/papers/69a75e40c6e9836116a28aa8 — DOI: https://doi.org/10.21037/tcr-2025-1218

Authors

P. Remiszewski

Medical University of Warsaw

Anna Czarnecka

National Institute of Oncology

Eryk Siedlecki

Medical University of Warsaw

Journals

Translational Cancer Research

Actions

Institutions

Polish Academy of Sciences

Medical University of Warsaw

The Maria Sklodowska-Curie National Research Institute of Oncology

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Introduction to animal modelling: factors and tools for choosing the optimal model for sarcoma research—a comprehensive literature review

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion