March 3, 2026Open Access

Could the telescoping effect and comorbidity with substance use disorders account for sex differences in the processes and therapeutic outcomes? A latent-class moderation analysis

Key Points

Females may experience higher readmission rates due to telescoping related to alcohol dependence and mood disorders.
In a study of sex differences, males showed greater needs for post-treatment care linked to impulse-control disorders.
This analysis employed latent class moderation analysis to evaluate therapeutic outcomes based on comorbidity with substance use disorders.
Tailored interventions can potentially improve outcomes by addressing specific needs based on gender differences.

Abstract

Telescoping and sex differences may contribute to higher readmission in females, particularly with alcohol dependence and mood or personality disorders. Males with impulse-control or childhood disorders may require more post-treatment care. Sex-specific interventions and moderation/latent class approaches may improve targeting.

Could the telescoping effect and comorbidity with substance use disorders account for sex differences in the processes and therapeutic outcomes? A latent-class moderation analysis

Key Points

Abstract

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